Fungal Pancolitis in an Immunocompetent Patient: A Case Report

Abstract

Normal gastrointestinal flora plays a crucial role in protecting against opportunistic pathogens, including bacteria and fungi. Fungal infection, in particular, may occur in patients whose commensal homeostasis is disrupted. Fungal colitis is a rare manifestation of fungal infection of the gastrointestinal tract, particularly in immunocompetent patients. This presents with a mortality rate of 50%, with Candida sp. being the most common causative agent. Evidence in this condition is lacking, and case reports can add to the collective information for generalizable information on this condition. This paper presents a rare case of a 63-year-old immunocompetent woman with fungal pancolitis, its presentation, examination, diagnosis, treatment, and response. Also discussed are the difficulties in diagnosing this rare condition, namely, its similar presentation to functional disorders.