Fanconi Syndrome Induced by Tenofovir in a Diabetic Patient with a History of Chronic Hepatitis B: A Case Report

Zeinab Saremi, Tahereh Fakharian


Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor and has been extensively used in the first-line treatment of viral infectious diseases such as chronic hepatitis B. Despite its good safety, the development of Fanconi syndrome is a rare adverse effect of long-term tenofovir therapy. Here, we report a case of a 62-year-old diabetic woman with a history of chronic hepatitis B who was exposed to tenofovir and developed drug-associated Fanconi syndrome. After discounting tenofovir, the patient's bone pain was markedly reduced.


Fanconi Syndrome ; Tenofovir ;Diabetic Patient ; Chronic Hepatitis B

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